
These two genes could play a large role in the evolution of humans. A bottleneck had occurred around 100,000 years ago that reduced the population of our ancestors to around five to 10,000, note researchers. The reason for this bottleneck is unknown; it could have been due to several combined factors, such as extreme climate change or a disease outbreak. The response to infectious diseases by turning off two genes could have protected a small group of Homo sapiens who then passed this mutation to their offspring and may be one factor in the evolution of modern ancestors, conclude researchers.
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